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Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target compounds. Here, the combination of optimizing precursor synthesis and balancing cofactor metabolism was adopted to improve tryptophan production in Escherich...

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Detalles Bibliográficos
Publicado en:Synth Syst Biotechnol
Main Authors: Li, Zhu, Ding, Dongqin, Wang, Huiying, Liu, Linxia, Fang, Huan, Chen, Tao, Zhang, Dawei
Formato: Artigo
Idioma:Inglês
Publicado: KeAi Publishing 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334480/
https://ncbi.nlm.nih.gov/pubmed/32671235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2020.06.009
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