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Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target compounds. Here, the combination of optimizing precursor synthesis and balancing cofactor metabolism was adopted to improve tryptophan production in Escherich...

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Detalhes bibliográficos
Publicado no:Synth Syst Biotechnol
Main Authors: Li, Zhu, Ding, Dongqin, Wang, Huiying, Liu, Linxia, Fang, Huan, Chen, Tao, Zhang, Dawei
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334480/
https://ncbi.nlm.nih.gov/pubmed/32671235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2020.06.009
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