Regulation of the RNA‐binding protein Smaug by the GPCR Smoothened via the kinase Fused

From fly to mammals, the Smaug/Samd4 family of prion‐like RNA‐binding proteins control gene expression by destabilizing and/or repressing the translation of numerous target transcripts. However, the regulation of its activity remains poorly understood. We show that Smaug's protein levels and mR...

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Pubblicato in:EMBO Rep
Autori principali: Bruzzone, Lucia, Argüelles, Camilla, Sanial, Matthieu, Miled, Samia, Alvisi, Giorgia, Gonçalves‐Antunes, Marina, Qasrawi, Fairouz, Holmgren, Robert A, Smibert, Craig A, Lipshitz, Howard D, Boccaccio, Graciela L, Plessis, Anne, Bécam, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332968/
https://ncbi.nlm.nih.gov/pubmed/32383557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948425
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