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Biophysical characterisation of the novel zinc binding property in Suppressor of Fused
Suppressor of Fused (SUFU) is a highly conserved protein that acts as a negative regulator of the Hedgehog (HH) signalling pathway, a major determinant of cell differentiation and proliferation. Therefore, SUFU deletion in mammals has devastating effects on embryo development. SUFU is part of a mult...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5593987/ https://ncbi.nlm.nih.gov/pubmed/28894158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11203-2 |
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