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p53, Cyclin-D1, β-catenin, APC and c-myc in Tumor Tissue from Colorectal and Gastric Cancer Patients with Suspected Lynch Syndrome by the Bethesda Criteria

Colorectal cancer (CRC) is one of the most frequent neoplasms worldwide, and up to 15% have a family history. Lynch syndrome (LS) is a hereditary cause of CRC and gastric (GC). Individuals with LS have mutations in mismatch genes repair. p53, cyclin D1, β-catenin, APC and c-myc proteins are involved...

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Podrobná bibliografie
Vydáno v:Asian Pac J Cancer Prev
Hlavní autoři: Marcolino, Tais Fernanda, Pimenta, Celia Aparecida Marques, Neto, Ricardo Artigiani, Castelo, Paula, Silva, Marcelo Souza, Forones, Nora Manoukian, Oshima, Celina Tizuko Fujiyama
Médium: Artigo
Jazyk:Inglês
Vydáno: West Asia Organization for Cancer Prevention 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332149/
https://ncbi.nlm.nih.gov/pubmed/32102509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2020.21.2.343
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