p53, Cyclin-D1, β-catenin, APC and c-myc in Tumor Tissue from Colorectal and Gastric Cancer Patients with Suspected Lynch Syndrome by the Bethesda Criteria

Colorectal cancer (CRC) is one of the most frequent neoplasms worldwide, and up to 15% have a family history. Lynch syndrome (LS) is a hereditary cause of CRC and gastric (GC). Individuals with LS have mutations in mismatch genes repair. p53, cyclin D1, β-catenin, APC and c-myc proteins are involved...

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Udgivet i:Asian Pac J Cancer Prev
Main Authors: Marcolino, Tais Fernanda, Pimenta, Celia Aparecida Marques, Neto, Ricardo Artigiani, Castelo, Paula, Silva, Marcelo Souza, Forones, Nora Manoukian, Oshima, Celina Tizuko Fujiyama
Format: Artigo
Sprog:Inglês
Udgivet: West Asia Organization for Cancer Prevention 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332149/
https://ncbi.nlm.nih.gov/pubmed/32102509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31557/APJCP.2020.21.2.343
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