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Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation

Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl(2)-induced aneurysm model, whereas Opg was found to promote su...

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Foilsithe in:PLoS One
Main Authors: Bumdelger, Batmunkh, Otani, Mikage, Karasaki, Kohei, Sakai, Chiemi, Ishida, Mari, Kokubo, Hiroki, Yoshizumi, Masao
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331998/
https://ncbi.nlm.nih.gov/pubmed/32614927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235553
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