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Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation

Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl(2)-induced aneurysm model, whereas Opg was found to promote su...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Bumdelger, Batmunkh, Otani, Mikage, Karasaki, Kohei, Sakai, Chiemi, Ishida, Mari, Kokubo, Hiroki, Yoshizumi, Masao
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331998/
https://ncbi.nlm.nih.gov/pubmed/32614927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235553
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