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Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation

Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl(2)-induced aneurysm model, whereas Opg was found to promote su...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Bumdelger, Batmunkh, Otani, Mikage, Karasaki, Kohei, Sakai, Chiemi, Ishida, Mari, Kokubo, Hiroki, Yoshizumi, Masao
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331998/
https://ncbi.nlm.nih.gov/pubmed/32614927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235553
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