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Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic–ischaemic brain injury: a single laboratory meta-analysis

Therapeutic hypothermia (HT) is standard care for term infants with hypoxic–ischaemic (HI) encephalopathy. However, the efficacy of HT in preclinical models, such as the Vannucci model of unilateral HI in the newborn rat, is often greater than that reported from clinical trials. Here, we report a me...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wood, Thomas R., Gundersen, Julia K., Falck, Mari, Maes, Elke, Osredkar, Damjan, Løberg, Else Marit, Sabir, Hemmen, Walløe, Lars, Thoresen, Marianne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331720/
https://ncbi.nlm.nih.gov/pubmed/32616806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67532-2
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