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Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia

Therapeutic hypothermia (HT) is standard care for moderate and severe neonatal hypoxic-ischaemic encephalopathy (HIE), the leading cause of permanent brain injury in term newborns. However, the optimal temperature for HT is still unknown, and few preclinical studies have compared multiple HT treatme...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wood, Thomas, Osredkar, Damjan, Puchades, Maja, Maes, Elke, Falck, Mari, Flatebø, Torun, Walløe, Lars, Sabir, Hemmen, Thoresen, Marianne
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800445/
https://ncbi.nlm.nih.gov/pubmed/26997257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23430
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