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Xenon Combined with Therapeutic Hypothermia Is Not Neuroprotective after Severe Hypoxia-Ischemia in Neonatal Rats

BACKGROUND: Therapeutic hypothermia (TH) is standard treatment following perinatal asphyxia in newborn infants. Experimentally, TH is neuroprotective after moderate hypoxia-ischemia (HI) in seven-day-old (P7) rats. However, TH is not neuroprotective after severe HI. After a moderate HI insult in new...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sabir, Hemmen, Osredkar, Damjan, Maes, Elke, Wood, Thomas, Thoresen, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890818/
https://ncbi.nlm.nih.gov/pubmed/27253085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156759
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