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Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis
Elevated levels of the inducible heat shock protein 70 (Hsp72) have been implicated in mammary tumorigenesis in histological investigations of human breast cancer. We therefore examined the role of Hsp72 in mice, using animals in which the hsp70 gene was inactivated. We used a spontaneous tumor syst...
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| Publié dans: | Oncogene |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7331470/ https://ncbi.nlm.nih.gov/pubmed/25659585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.1 |
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