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T cell activation by HSP70 vaccine requires TLR signaling and scavenger receptor SREC-1

HSP70 isolated from tumor-dendritic cell fusions (HSP70.PC-F) induces potent anti-tumor immunity and prevents growth of such tumors. In the present study, we have examined mechanisms underlying such anti-tumor activity of the HSP70.PC-F vaccine. The degree of anti-tumor immunity induced by HSP70.PC-...

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Bibliographic Details
Main Authors: Gong, Jianlin, Zhu, Bangmin, Murshid, Ayesha, Adachi, Hideki, Song, Baizheng, Lee, Allegra, Liu, Chunlei, Calderwood, Stuart K.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754732/
https://ncbi.nlm.nih.gov/pubmed/19641135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901235
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