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Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I

Molecular chaperones such as heat shock protein 90 (Hsp90) have been shown to form complexes with tumor antigens and can be used to prepare anticancer vaccines largely due to this property. Earlier studies had suggested that, mice immunized with a molecular chaperone based vaccine derived from tumor...

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Detalhes bibliográficos
Publicado no:Immunobiology
Main Authors: Murshid, Ayesha, Gong, Jianlin, Calderwood, Stuart K
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886339/
https://ncbi.nlm.nih.gov/pubmed/25155057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2014.08.001
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