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Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I

Molecular chaperones such as heat shock protein 90 (Hsp90) have been shown to form complexes with tumor antigens and can be used to prepare anticancer vaccines largely due to this property. Earlier studies had suggested that, mice immunized with a molecular chaperone based vaccine derived from tumor...

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Dettagli Bibliografici
Pubblicato in:Immunobiology
Autori principali: Murshid, Ayesha, Gong, Jianlin, Calderwood, Stuart K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886339/
https://ncbi.nlm.nih.gov/pubmed/25155057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2014.08.001
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