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An HSP70-based vaccine with enhanced immunogenicity for clinical use
In previous studies we have shown that HSP70-peptide complexes (HSP70.PC) derived from the fusion of dendritic cells (DC) to tumor cells (HSP70.PC-F) possess superior properties compared to HSP70.PC from tumor cells. HSP70.PC-F are more effective in stimulation of DC maturation and induction of CTL...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911119/ https://ncbi.nlm.nih.gov/pubmed/19949080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902255 |
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