High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells

BACKGROUND: Progesterone receptor (PR) affects immunomodulation, and lack of PR in osteoprogenitor cells primarily affects pathways associated with immunomodulation, especially in males. In this study, we selectively deleted PR from osteoprogenitor cells using Prx1-Cre to evaluate the tissue-specifi...

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Publicado en:Arthritis Res Ther
Autores principales: Liu, Lixian, Jia, Junjing, Jiang, Min, Liu, Xueping, Dai, Chenling, Wise, Barton L., Lane, Nancy E., Yao, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331177/
https://ncbi.nlm.nih.gov/pubmed/32616012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02242-8
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