High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells

BACKGROUND: Progesterone receptor (PR) affects immunomodulation, and lack of PR in osteoprogenitor cells primarily affects pathways associated with immunomodulation, especially in males. In this study, we selectively deleted PR from osteoprogenitor cells using Prx1-Cre to evaluate the tissue-specifi...

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Pubblicato in:Arthritis Res Ther
Autori principali: Liu, Lixian, Jia, Junjing, Jiang, Min, Liu, Xueping, Dai, Chenling, Wise, Barton L., Lane, Nancy E., Yao, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331177/
https://ncbi.nlm.nih.gov/pubmed/32616012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02242-8
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