High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells

BACKGROUND: Progesterone receptor (PR) affects immunomodulation, and lack of PR in osteoprogenitor cells primarily affects pathways associated with immunomodulation, especially in males. In this study, we selectively deleted PR from osteoprogenitor cells using Prx1-Cre to evaluate the tissue-specifi...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Liu, Lixian, Jia, Junjing, Jiang, Min, Liu, Xueping, Dai, Chenling, Wise, Barton L., Lane, Nancy E., Yao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331177/
https://ncbi.nlm.nih.gov/pubmed/32616012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02242-8
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