Selective inhibition of progesterone receptor in osteochondral progenitor cells, but not in mature chondrocytes, modulated subchondral bone structures

OBJECTIVE. The presence or relative proportion of progesterone nuclear receptors (PR) in different tissues may contribute to sexual dimorphism in these tissues. PR is expressed in chondrocytes, but its function is mostly unknown. We hypothesized that the PR may regulate chondrocyte metabolism and af...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Dai, Chenlin, Jia, Junjing, Kot, Alexander, Liu, Xueping, Liu, Lixian, Jiang, Min, Lane, Nancy E., Wise, Barton L., Yao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006606/
https://ncbi.nlm.nih.gov/pubmed/31863959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.115196
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