Selective inhibition of progesterone receptor in osteochondral progenitor cells, but not in mature chondrocytes, modulated subchondral bone structures

OBJECTIVE. The presence or relative proportion of progesterone nuclear receptors (PR) in different tissues may contribute to sexual dimorphism in these tissues. PR is expressed in chondrocytes, but its function is mostly unknown. We hypothesized that the PR may regulate chondrocyte metabolism and af...

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Dades bibliogràfiques
Publicat a:Bone
Autors principals: Dai, Chenlin, Jia, Junjing, Kot, Alexander, Liu, Xueping, Liu, Lixian, Jiang, Min, Lane, Nancy E., Wise, Barton L., Yao, Wei
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006606/
https://ncbi.nlm.nih.gov/pubmed/31863959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.115196
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