Lower T Regulatory and Th17 Cell Populations Predicted by RT-PCR-Amplified FOXP3 and RORγt Genes Are Not Rare in Patients With Primary Immunodeficiency Diseases

Deficiencies in T regulatory (Treg) and Th17 cells attenuate peripheral tolerance and the IL-17 family of cytokines, contributing to autoimmune disorders and opportunistic (fungal) infections, respectively. Because of limited blood samples from patients with primary immunodeficiency diseases (PIDs),...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lee, Wen-I, Huang, Jing-Long, Lin, Syh-Jae, Yeh, Kuo-Wei, Chen, Li-Chen, Ou, Liang-Shiou, Yao, Tsung-Chieh, Jaing, Tang-Her, Shih, Ying-Fan, Wu, Chao-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330141/
https://ncbi.nlm.nih.gov/pubmed/32670274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01111
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