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Cystathionine β-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs(−/−) mice and thrombosis-prone CBS(−/−) humans
Cystathionine β-synthase (CBS)-deficient patients are prone to vascular thrombosis. In contrast, Cbs(−/−) mice show no abnormalities in blood coagulation. To identify molecular basis underlying these disparately different thrombotic phenotypes, we analyzed plasma proteomes of Cbs(−/−) vs. Cbs(+/+) m...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7329814/ https://ncbi.nlm.nih.gov/pubmed/32612202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67672-5 |
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