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Genetic Attenuation of Paraoxonase 1 Activity Induces Proatherogenic Changes in Plasma Proteomes of Mice and Humans

High-density lipoprotein (HDL), in addition to promoting reverse cholesterol transport, possesses anti-inflammatory, antioxidative, and antithrombotic activities. Paraoxonase 1 (PON1), carried on HDL in the blood, can contribute to these antiatherogenic activities. The PON1-Q192R polymorphism involv...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Sikora, Marta, Bretes, Ewa, Perła-Kaján, Joanna, Lewandowska, Izabela, Marczak, Łukasz, Jakubowski, Hieronim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7761039/
https://ncbi.nlm.nih.gov/pubmed/33260536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121198
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