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Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells
The absence of alloantibodies is a feature of transplantation tolerance. Although the lack of T cell help has been evoked to explain this absence, herein we provide evidence for B cell–intrinsic tolerance mechanisms. Using a murine model of heart tolerance, we showed that alloreactive B cells were n...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7329196/ https://ncbi.nlm.nih.gov/pubmed/32452834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132814 |
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