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Tracing donor-MHC Class II reactive B cells in mouse cardiac transplantation: delayed CTLA4-Ig treatment prevents memory alloreactive B cell generation

BACKGROUND: The dual role of B cells as drivers and suppressors of the immune responses have underscored the need to trace the fate of B cells recognizing donor MHC Class I and Class II following allograft transplantation. METHODS: In this study we used donor Class II tetramers to trace the fate of...

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Publicado en:Transplantation
Autores principales: Yang, Jinghui, Chen, Jianjun, Young, James, Wang, Qiang, Yin, Dengping, Sciammas, Roger, Chong, Anita S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961602/
https://ncbi.nlm.nih.gov/pubmed/27362308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001253
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