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A genome-wide and cotranscriptional suppressor of R loops
R loops arise from hybridization of RNA transcripts with template DNA during transcription. Unrepaired R loops lead to transcription–replication collisions, causing DNA damage and genomic instability. In this issue of Genes & Development, Pérez-Calero and colleagues (pp. 898–912) identify UAP56...
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| Udgivet i: | Genes Dev |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7328514/ https://ncbi.nlm.nih.gov/pubmed/32611612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.339861.120 |
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