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Cotranscriptional R-loop formation by Mfd involves topological partitioning of DNA

R-loops are nucleic acid hybrids which form when an RNA invades duplex DNA to pair with its template sequence. Although they are implicated in a growing number of gene regulatory processes, their mechanistic origins remain unclear. We here report real-time observations of cotranscriptional R-loop fo...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Portman, James R., Brouwer, Gwendolyn M., Bollins, Jack, Savery, Nigel J., Strick, Terence R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053947/
https://ncbi.nlm.nih.gov/pubmed/33827922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019630118
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