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Posttranslational Regulation and Conformational Plasticity of PTEN
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor that is frequently down-modulated in human cancer. PTEN inhibits the phosphatidylinositol 3-phosphate kinase (PI3K)/AKT pathway through its lipid phosphatase activity. Multiple PI3K/AKT-independent actions of PTEN,...
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| Pubblicato in: | Cold Spring Harb Perspect Med |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7328454/ https://ncbi.nlm.nih.gov/pubmed/31932468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036095 |
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