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Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins
The tumour suppressor PTEN (phosphatase and tensin deleted on chromosome 10) regulates major cellular functions via lipid phosphatase-dependent and -independent mechanisms. Despite its fundamental pathophysiological importance, how PTEN's cellular activity is regulated has only been partially e...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155309/ https://ncbi.nlm.nih.gov/pubmed/21642958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.178 |
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