Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins

The tumour suppressor PTEN (phosphatase and tensin deleted on chromosome 10) regulates major cellular functions via lipid phosphatase-dependent and -independent mechanisms. Despite its fundamental pathophysiological importance, how PTEN's cellular activity is regulated has only been partially e...

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Detalhes bibliográficos
Main Authors: Lima-Fernandes, Evelyne, Enslen, Hervé, Camand, Emeline, Kotelevets, Larissa, Boularan, Cédric, Achour, Lamia, Benmerah, Alexandre, Gibson, Lucien C D, Baillie, George S, Pitcher, Julie A, Chastre, Eric, Etienne-Manneville, Sandrine, Marullo, Stefano, Scott, Mark G H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155309/
https://ncbi.nlm.nih.gov/pubmed/21642958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.178
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