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Distinct functional outputs of PTEN signalling are controlled by dynamic association with β-arrestins

The tumour suppressor PTEN (phosphatase and tensin deleted on chromosome 10) regulates major cellular functions via lipid phosphatase-dependent and -independent mechanisms. Despite its fundamental pathophysiological importance, how PTEN's cellular activity is regulated has only been partially e...

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Bibliografski detalji
Glavni autori: Lima-Fernandes, Evelyne, Enslen, Hervé, Camand, Emeline, Kotelevets, Larissa, Boularan, Cédric, Achour, Lamia, Benmerah, Alexandre, Gibson, Lucien C D, Baillie, George S, Pitcher, Julie A, Chastre, Eric, Etienne-Manneville, Sandrine, Marullo, Stefano, Scott, Mark G H
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155309/
https://ncbi.nlm.nih.gov/pubmed/21642958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.178
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