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The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
To analyze the implication of PTEN in the control of tumor cell invasiveness, the canine kidney epithelial cell lines MDCKras-f and MDCKts-src, expressing activated Ras and a temperature-sensitive v-Src tyrosine kinase, respectively, were transfected with PTEN expression vectors. Likewise, the human...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2199329/ https://ncbi.nlm.nih.gov/pubmed/11756467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200105109 |
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