The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness

To analyze the implication of PTEN in the control of tumor cell invasiveness, the canine kidney epithelial cell lines MDCKras-f and MDCKts-src, expressing activated Ras and a temperature-sensitive v-Src tyrosine kinase, respectively, were transfected with PTEN expression vectors. Likewise, the human...

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Detalhes bibliográficos
Main Authors: Kotelevets, Larissa, van Hengel, Jolanda, Bruyneel, Erik, Mareel, Marc, van Roy, Frans, Chastre, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199329/
https://ncbi.nlm.nih.gov/pubmed/11756467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200105109
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