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The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness

To analyze the implication of PTEN in the control of tumor cell invasiveness, the canine kidney epithelial cell lines MDCKras-f and MDCKts-src, expressing activated Ras and a temperature-sensitive v-Src tyrosine kinase, respectively, were transfected with PTEN expression vectors. Likewise, the human...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kotelevets, Larissa, van Hengel, Jolanda, Bruyneel, Erik, Mareel, Marc, van Roy, Frans, Chastre, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199329/
https://ncbi.nlm.nih.gov/pubmed/11756467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200105109
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