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The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness

To analyze the implication of PTEN in the control of tumor cell invasiveness, the canine kidney epithelial cell lines MDCKras-f and MDCKts-src, expressing activated Ras and a temperature-sensitive v-Src tyrosine kinase, respectively, were transfected with PTEN expression vectors. Likewise, the human...

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書誌詳細
主要な著者: Kotelevets, Larissa, van Hengel, Jolanda, Bruyneel, Erik, Mareel, Marc, van Roy, Frans, Chastre, Eric
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199329/
https://ncbi.nlm.nih.gov/pubmed/11756467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200105109
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