End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

BACKGROUND: The molecular mechanisms underlying chronic kidney disease (CKD) transition to end-stage renal disease (ESRD) and CKD acceleration of cardiovascular and other tissue inflammations remain poorly determined. METHODS: We conducted a comprehensive data analyses on 7 microarray datasets in pe...

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Publié dans:Redox Biol
Auteurs principaux: Zhang, Ruijing, Saredy, Jason, Shao, Ying, Yao, Tian, Liu, Lu, Saaoud, Fatma, Yang, William Y., Sun, Yu, Johnson, Candice, Drummer, Charles, Fu, Hangfei, Lu, Yifan, Xu, Keman, Liu, Ming, Wang, Jirong, Cutler, Elizabeth, Yu, Daohai, Jiang, Xiaohua, Li, Yafeng, Li, Rongshan, Wang, Lihua, Choi, Eric T., Wang, Hong, Yang, Xiaofeng
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Articles from the Special Issue on Redox Signalling and Cardiovascular Disease; Edited by Christopher Kevil and Yabing Chen
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327976/
https://ncbi.nlm.nih.gov/pubmed/32179051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101460
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