Enhanced intestinal lymphatic absorption of saquinavir through supersaturated self-microemulsifying drug delivery systems

The therapeutic potential of saquinavir, a specific inhibitor of human immunodeficiency virus (HIV)-1 and HIV-2 protease enzymes, has been largely limited because of a low solubility and consequnt low bioavailability. Thus, we aimed to design a supersaturated self-microemulsifying drug delivery syst...

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Veröffentlicht in:Asian J Pharm Sci
Hauptverfasser: Jo, Kanghee, Kim, Hyeongmin, Khadka, Prakash, Jang, Taejun, Kim, Soo Jin, Hwang, Seong-Ha, Lee, Jaehwi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shenyang Pharmaceutical University 2020
Schlagworte:
Research article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327769/
https://ncbi.nlm.nih.gov/pubmed/32636951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.11.009
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