The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant Staphylococcus aureus

Resistance or tolerance to traditional antibiotics is a challenging issue in antimicrobial chemotherapy. Moreover, traditional bactericidal antibiotics kill only actively growing bacterial cells, whereas nongrowing metabolically inactive cells are tolerant to and therefore “persist” in the presence...

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Pubblicato in:mBio
Autori principali: Kim, Wooseong, Zou, Guijin, Pan, Wen, Fricke, Nico, Faizi, Hammad A., Kim, Soo Min, Khader, Rajamohammed, Li, Silei, Lee, Kiho, Escorba, Iliana, Vlahovska, Petia M., Gao, Huajian, Ausubel, Frederick M., Mylonakis, Eleftherios
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327171/
https://ncbi.nlm.nih.gov/pubmed/32605985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01140-20
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