A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus

Treatment of Staphylococcus aureus infections is complicated by the development of antibiotic tolerance, a consequence of the ability of S. aureus to enter into a nongrowing, dormant state in which the organisms are referred to as persisters. We report that the clinically approved anthelmintic agent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kim, Wooseong, Zou, Guijin, Hari, Taylor P. A., Wilt, Ingrid K., Zhu, Wenpeng, Galle, Nicolas, Faizi, Hammad A., Hendricks, Gabriel L., Tori, Katerina, Pan, Wen, Huang, Xiaowen, Steele, Andrew D., Csatary, Erika E., Dekarske, Madeline M., Rosen, Jake L., Ribeiro, Noelly de Queiroz, Lee, Kiho, Port, Jenna, Fuchs, Beth Burgwyn, Vlahovska, Petia M., Wuest, William M., Gao, Huajian, Ausubel, Frederick M., Mylonakis, Eleftherios
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697817/
https://ncbi.nlm.nih.gov/pubmed/31358625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904700116
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