Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic scarring disease in which aging, environmental exposure(s) and genetic susceptibility have been implicated in disease pathogenesis, however, the causes and mechanisms of the progressive fibrotic cascade are still poorly understood. As epithelial–mesen...

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Bibliografiset tiedot
Julkaisussa:Cell Death Discov
Päätekijät: Conforti, Franco, Ridley, Robert, Brereton, Christopher, Alzetani, Aiman, Johnson, Benjamin, Marshall, Ben G., Fletcher, Sophie V., Ottensmeier, Christian H., Richeldi, Luca, Skipp, Paul, Wang, Yihua, Jones, Mark G., Davies, Donna E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327077/
https://ncbi.nlm.nih.gov/pubmed/32637156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0289-9
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