Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic scarring disease in which aging, environmental exposure(s) and genetic susceptibility have been implicated in disease pathogenesis, however, the causes and mechanisms of the progressive fibrotic cascade are still poorly understood. As epithelial–mesen...

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Publicat a:Cell Death Discov
Autors principals: Conforti, Franco, Ridley, Robert, Brereton, Christopher, Alzetani, Aiman, Johnson, Benjamin, Marshall, Ben G., Fletcher, Sophie V., Ottensmeier, Christian H., Richeldi, Luca, Skipp, Paul, Wang, Yihua, Jones, Mark G., Davies, Donna E.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327077/
https://ncbi.nlm.nih.gov/pubmed/32637156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0289-9
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