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Supervised learning of gene-regulatory networks based on graph distance profiles of transcriptomics data

Characterisation of gene-regulatory network (GRN) interactions provides a stepping stone to understanding how genes affect cellular phenotypes. Yet, despite advances in profiling technologies, GRN reconstruction from gene expression data remains a pressing problem in systems biology. Here, we devise...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327016/
https://ncbi.nlm.nih.gov/pubmed/32606380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-020-0140-1
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