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A Synthetic Reporter for Probing Mistranslation in Living Cells
Aminoacyl-tRNA synthetases (AARSs) play key roles in maintaining high fidelity of protein synthesis. They charge cognate tRNAs with corresponding amino acids and hydrolyze mischarged tRNAs by editing mechanisms. Impairment of AARS editing activities can reduce the accuracy of tRNA aminoacylation to...
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| Publicado no: | Front Bioeng Biotechnol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7326783/ https://ncbi.nlm.nih.gov/pubmed/32671035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00623 |
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