Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71

PURPOSE: To study the potential effect of a gene therapy, designed to rescue the expression of dystrophin Dp71 in the retinas of Dp71-null mice, on retinal physiology. METHODS: We recorded electroretinograms (ERGs) in Dp71-null and wild-type littermate mice. In dark-adapted eyes, responses to flashe...

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Dettagli Bibliografici
Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Barboni, Mirella Telles Salgueiro, Vaillend, Cyrille, Joachimsthaler, Anneka, Liber, André Maurício Passos, Khabou, Hanen, Roux, Michel J., Vacca, Ophélie, Vignaud, Lucile, Dalkara, Deniz, Guillonneau, Xavier, Ventura, Dora Fix, Rendon, Alvaro, Kremers, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2020
Soggetti:
Visual Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326481/
https://ncbi.nlm.nih.gov/pubmed/32049345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.2.11
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