Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71

PURPOSE: To study the potential effect of a gene therapy, designed to rescue the expression of dystrophin Dp71 in the retinas of Dp71-null mice, on retinal physiology. METHODS: We recorded electroretinograms (ERGs) in Dp71-null and wild-type littermate mice. In dark-adapted eyes, responses to flashe...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Barboni, Mirella Telles Salgueiro, Vaillend, Cyrille, Joachimsthaler, Anneka, Liber, André Maurício Passos, Khabou, Hanen, Roux, Michel J., Vacca, Ophélie, Vignaud, Lucile, Dalkara, Deniz, Guillonneau, Xavier, Ventura, Dora Fix, Rendon, Alvaro, Kremers, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2020
Assuntos:
Visual Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326481/
https://ncbi.nlm.nih.gov/pubmed/32049345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.2.11
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