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Sequence independent self-assembly of germ granule mRNAs into homotypic clusters

mRNAs enriched in membraneless condensates provide functional compartmentalization within cells. The mechanisms that recruit transcripts to condensates are under intense study, however how mRNAs organize once they reach a granule remains poorly understood. Here, we report on a self-sorting mechanism...

詳細記述

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書誌詳細
出版年:Mol Cell
主要な著者: Trcek, Tatjana, Douglas, Tyler E., Grosch, Markus, Yin, Yandong, Eagle, Whitby V.I., Gavis, Elizabeth R., Shroff, Hari, Rothenberg, Eli, Lehmann, Ruth
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325742/
https://ncbi.nlm.nih.gov/pubmed/32464092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.05.008
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