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Sequence independent self-assembly of germ granule mRNAs into homotypic clusters

mRNAs enriched in membraneless condensates provide functional compartmentalization within cells. The mechanisms that recruit transcripts to condensates are under intense study, however how mRNAs organize once they reach a granule remains poorly understood. Here, we report on a self-sorting mechanism...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Trcek, Tatjana, Douglas, Tyler E., Grosch, Markus, Yin, Yandong, Eagle, Whitby V.I., Gavis, Elizabeth R., Shroff, Hari, Rothenberg, Eli, Lehmann, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325742/
https://ncbi.nlm.nih.gov/pubmed/32464092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.05.008
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