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Sequence independent self-assembly of germ granule mRNAs into homotypic clusters

mRNAs enriched in membraneless condensates provide functional compartmentalization within cells. The mechanisms that recruit transcripts to condensates are under intense study, however how mRNAs organize once they reach a granule remains poorly understood. Here, we report on a self-sorting mechanism...

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Publicado en:Mol Cell
Autores principales: Trcek, Tatjana, Douglas, Tyler E., Grosch, Markus, Yin, Yandong, Eagle, Whitby V.I., Gavis, Elizabeth R., Shroff, Hari, Rothenberg, Eli, Lehmann, Ruth
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325742/
https://ncbi.nlm.nih.gov/pubmed/32464092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.05.008
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