Sequence independent self-assembly of germ granule mRNAs into homotypic clusters

mRNAs enriched in membraneless condensates provide functional compartmentalization within cells. The mechanisms that recruit transcripts to condensates are under intense study, however how mRNAs organize once they reach a granule remains poorly understood. Here, we report on a self-sorting mechanism...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Trcek, Tatjana, Douglas, Tyler E., Grosch, Markus, Yin, Yandong, Eagle, Whitby V.I., Gavis, Elizabeth R., Shroff, Hari, Rothenberg, Eli, Lehmann, Ruth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325742/
https://ncbi.nlm.nih.gov/pubmed/32464092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.05.008
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