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Methods to Study the Structure and Catalytic Activity of cis-Splicing Inteins

The autocatalytic process of protein splicing is facilitated by an intein, which interrupts flanking polypeptides called exteins. The mechanism of protein splicing has been studied by overexpression in E. coli of intein fusion proteins with nonnative exteins. Inteins can be used to generate reactive...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Zhao, Jing, Du, Zhenming, Wang, Chunyu, Mills, Kenneth V.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325523/
https://ncbi.nlm.nih.gov/pubmed/32144663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-0434-2_4
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