Assessment of Placental Disposition of Infliximab and Etanercept in Women With Autoimmune Diseases and in the Ex Vivo Perfused Placenta

Tumor necrosis factor (TNF) inhibitors are increasingly applied during pregnancy without clear knowledge of the impact on placenta and fetus. We assessed placental transfer and exposure to infliximab (n = 3) and etanercept (n = 3) in women with autoimmune diseases. Furthermore, we perfused healthy t...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Eliesen, Gaby A. M., van Drongelen, Joris, van Hove, Hedwig, Kooijman, Nina I., van den Broek, Petra, de Vries, Annick, Roeleveld, Nel, Russel, Frans G. M., Greupink, Rick
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325311/
https://ncbi.nlm.nih.gov/pubmed/32153014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1827
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