Assessment of Placental Disposition of Infliximab and Etanercept in Women With Autoimmune Diseases and in the Ex Vivo Perfused Placenta

Tumor necrosis factor (TNF) inhibitors are increasingly applied during pregnancy without clear knowledge of the impact on placenta and fetus. We assessed placental transfer and exposure to infliximab (n = 3) and etanercept (n = 3) in women with autoimmune diseases. Furthermore, we perfused healthy t...

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Dades bibliogràfiques
Publicat a:Clin Pharmacol Ther
Autors principals: Eliesen, Gaby A. M., van Drongelen, Joris, van Hove, Hedwig, Kooijman, Nina I., van den Broek, Petra, de Vries, Annick, Roeleveld, Nel, Russel, Frans G. M., Greupink, Rick
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325311/
https://ncbi.nlm.nih.gov/pubmed/32153014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1827
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