Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients

Ulcerative Colitis (UC) is an inflammatory bowel disease typically affecting the colon. Patients with active UC have elevated tumor necrosis factor (TNF) concentrations in serum and colonic tissue. Infliximab is a monoclonal antibody directed against TNF and binds with high affinity. Target-mediated...

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Vydáno v:J Pharmacokinet Pharmacodyn
Hlavní autoři: Berends, Sophie E., van Steeg, Tamara J., Ahsman, Maurice J., Singh, Sharat, Brandse, Johannan F., D’Haens, Geert R. A. M., Mathôt, Ron A. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2019
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868113/
https://ncbi.nlm.nih.gov/pubmed/31489538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-019-09652-5
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