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Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients
Ulcerative Colitis (UC) is an inflammatory bowel disease typically affecting the colon. Patients with active UC have elevated tumor necrosis factor (TNF) concentrations in serum and colonic tissue. Infliximab is a monoclonal antibody directed against TNF and binds with high affinity. Target-mediated...
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| Publicado no: | J Pharmacokinet Pharmacodyn |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868113/ https://ncbi.nlm.nih.gov/pubmed/31489538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-019-09652-5 |
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