Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients

Ulcerative Colitis (UC) is an inflammatory bowel disease typically affecting the colon. Patients with active UC have elevated tumor necrosis factor (TNF) concentrations in serum and colonic tissue. Infliximab is a monoclonal antibody directed against TNF and binds with high affinity. Target-mediated...

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Dettagli Bibliografici
Pubblicato in:J Pharmacokinet Pharmacodyn
Autori principali: Berends, Sophie E., van Steeg, Tamara J., Ahsman, Maurice J., Singh, Sharat, Brandse, Johannan F., D’Haens, Geert R. A. M., Mathôt, Ron A. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2019
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868113/
https://ncbi.nlm.nih.gov/pubmed/31489538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-019-09652-5
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