Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients

Ulcerative Colitis (UC) is an inflammatory bowel disease typically affecting the colon. Patients with active UC have elevated tumor necrosis factor (TNF) concentrations in serum and colonic tissue. Infliximab is a monoclonal antibody directed against TNF and binds with high affinity. Target-mediated...

詳細記述

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書誌詳細
出版年:J Pharmacokinet Pharmacodyn
主要な著者: Berends, Sophie E., van Steeg, Tamara J., Ahsman, Maurice J., Singh, Sharat, Brandse, Johannan F., D’Haens, Geert R. A. M., Mathôt, Ron A. A.
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2019
主題:
Original Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868113/
https://ncbi.nlm.nih.gov/pubmed/31489538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-019-09652-5
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