Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients

Ulcerative Colitis (UC) is an inflammatory bowel disease typically affecting the colon. Patients with active UC have elevated tumor necrosis factor (TNF) concentrations in serum and colonic tissue. Infliximab is a monoclonal antibody directed against TNF and binds with high affinity. Target-mediated...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Pharmacokinet Pharmacodyn
Main Authors: Berends, Sophie E., van Steeg, Tamara J., Ahsman, Maurice J., Singh, Sharat, Brandse, Johannan F., D’Haens, Geert R. A. M., Mathôt, Ron A. A.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2019
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868113/
https://ncbi.nlm.nih.gov/pubmed/31489538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-019-09652-5
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