SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients

SARS-CoV-2, the causative agent of COVID-19, emerged at the end of 2019 and by mid-June 2020, the virus has spread to at least 215 countries, caused more than 8,000,000 confirmed infections and over 450,000 deaths, and overwhelmed healthcare systems worldwide. Like SARS-CoV, which emerged in 2002 an...

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Publicat a:bioRxiv
Autors principals: Klimstra, William B., Tilston-Lunel, Natasha L., Nambulli, Sham, Boslett, James, McMillen, Cynthia M., Gilliland, Theron, Dunn, Matthew D., Sun, Chengqun, Wheeler, Sarah E, Wells, Alan, Hartman, Amy L., McElroy, Anita K., Reed, Douglas S., Rennick, Linda J., Duprex, W. Paul
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325173/
https://ncbi.nlm.nih.gov/pubmed/32607507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.19.154930
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