SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts

Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19) pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) model is a critical step in the process. Infection of African green monkeys (AGM) with a low passage human isolate of SARS-CoV-2...

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Publicado no:PLoS Pathog
Main Authors: Hartman, Amy L., Nambulli, Sham, McMillen, Cynthia M., White, Alexander G., Tilston-Lunel, Natasha Louise, Albe, Joseph R., Cottle, Emily, Dunn, Matthew D., Frye, L. James, Gilliland, Theron H., Olsen, Emily L., O’Malley, Katherine J., Schwarz, Madeline M., Tomko, Jaime A., Walker, Reagan C., Xia, Mengying, Hartman, Matthew S., Klein, Edwin, Scanga, Charles A., Flynn, JoAnne L., Klimstra, William B., McElroy, Anita K., Reed, Douglas S., Duprex, W. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535860/
https://ncbi.nlm.nih.gov/pubmed/32946524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008903
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