CB(1) Cannabinoid Receptors Stimulate Gβγ-GRK2-Mediated FAK Phosphorylation at Tyrosine 925 to Regulate ERK Activation Involving Neuronal Focal Adhesions

CB(1) cannabinoid receptors (CB(1)) are abundantly expressed in the nervous system where they regulate focal adhesion kinase (FAK) and the mitogen-activated protein kinases (MAPK) extracellular signal-regulated kinase 1 and 2 (ERK1/2). However, the role of CB(1)-stimulated FAK 925 tyrosine phosphory...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Dalton, George D., Carney, Skyla T., Marshburn, Jamie D., Norford, Derek C., Howlett, Allyn C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324865/
https://ncbi.nlm.nih.gov/pubmed/32655375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00176
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