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CB(1) Cannabinoid Receptors Stimulate Gβγ-GRK2-Mediated FAK Phosphorylation at Tyrosine 925 to Regulate ERK Activation Involving Neuronal Focal Adhesions

CB(1) cannabinoid receptors (CB(1)) are abundantly expressed in the nervous system where they regulate focal adhesion kinase (FAK) and the mitogen-activated protein kinases (MAPK) extracellular signal-regulated kinase 1 and 2 (ERK1/2). However, the role of CB(1)-stimulated FAK 925 tyrosine phosphory...

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Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Dalton, George D., Carney, Skyla T., Marshburn, Jamie D., Norford, Derek C., Howlett, Allyn C.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324865/
https://ncbi.nlm.nih.gov/pubmed/32655375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00176
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